ES436648A1 - Un procedimiento para la preparacion de compuestos tienilo ytietilo. - Google Patents
Un procedimiento para la preparacion de compuestos tienilo ytietilo.Info
- Publication number
- ES436648A1 ES436648A1 ES436648A ES436648A ES436648A1 ES 436648 A1 ES436648 A1 ES 436648A1 ES 436648 A ES436648 A ES 436648A ES 436648 A ES436648 A ES 436648A ES 436648 A1 ES436648 A1 ES 436648A1
- Authority
- ES
- Spain
- Prior art keywords
- ureas
- tertiary
- alkyl
- substituted
- thietyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 235000013877 carbamide Nutrition 0.000 title abstract 5
- 150000003672 ureas Chemical class 0.000 title abstract 4
- 125000001544 thienyl group Chemical group 0.000 title abstract 2
- 229940030600 antihypertensive agent Drugs 0.000 title 1
- 239000002220 antihypertensive agent Substances 0.000 title 1
- ZJEBGSGYSRSENA-UHFFFAOYSA-N 1-tert-butyl-3-(2,3-dihydrothiophen-4-yl)urea Chemical compound CC(C)(C)NC(=O)NC1=CSCC1 ZJEBGSGYSRSENA-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
- C07D331/04—Four-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
- C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46169974A | 1974-04-17 | 1974-04-17 | |
US05/555,307 US4009847A (en) | 1974-04-17 | 1975-03-11 | 1-Tertiary-alkyl-3-(substituted thienyl)ureas and 1-tertiary-alkyl-3-(substituted thietyl)ureas as antihypertensive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ES436648A1 true ES436648A1 (es) | 1977-08-01 |
Family
ID=27040095
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES436648A Expired ES436648A1 (es) | 1974-04-17 | 1975-04-16 | Un procedimiento para la preparacion de compuestos tienilo ytietilo. |
Country Status (21)
Country | Link |
---|---|
US (1) | US4009847A (en]) |
JP (1) | JPS50148349A (en]) |
AR (1) | AR208545A1 (en]) |
CA (1) | CA1047042A (en]) |
CH (1) | CH611292A5 (en]) |
DD (1) | DD117223A5 (en]) |
DE (1) | DE2516554A1 (en]) |
DK (1) | DK164175A (en]) |
ES (1) | ES436648A1 (en]) |
FI (1) | FI751128A7 (en]) |
FR (1) | FR2267773B1 (en]) |
GB (1) | GB1461209A (en]) |
HU (1) | HU173052B (en]) |
IE (1) | IE41143B1 (en]) |
IL (1) | IL47095A (en]) |
LU (1) | LU72306A1 (en]) |
NL (1) | NL7504570A (en]) |
NO (1) | NO144071C (en]) |
PH (1) | PH11722A (en]) |
SE (1) | SE417965B (en]) |
YU (1) | YU96075A (en]) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4156738A (en) * | 1977-10-07 | 1979-05-29 | E. I. Du Pont De Nemours And Company | Ureidonitriles useful as antihypertensives |
US6344476B1 (en) | 1997-05-23 | 2002-02-05 | Bayer Corporation | Inhibition of p38 kinase activity by aryl ureas |
US6187799B1 (en) * | 1997-05-23 | 2001-02-13 | Onyx Pharmaceuticals | Inhibition of raf kinase activity using aryl ureas |
US7329670B1 (en) * | 1997-12-22 | 2008-02-12 | Bayer Pharmaceuticals Corporation | Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas |
US7517880B2 (en) * | 1997-12-22 | 2009-04-14 | Bayer Pharmaceuticals Corporation | Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas |
US20080300281A1 (en) * | 1997-12-22 | 2008-12-04 | Jacques Dumas | Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas |
US20080269265A1 (en) * | 1998-12-22 | 2008-10-30 | Scott Miller | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas |
US7928239B2 (en) | 1999-01-13 | 2011-04-19 | Bayer Healthcare Llc | Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas |
WO2000042012A1 (en) | 1999-01-13 | 2000-07-20 | Bayer Corporation | φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS |
WO2000041698A1 (en) * | 1999-01-13 | 2000-07-20 | Bayer Corporation | φ-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS |
US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
US7351834B1 (en) | 1999-01-13 | 2008-04-01 | Bayer Pharmaceuticals Corporation | ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
US7235576B1 (en) | 2001-01-12 | 2007-06-26 | Bayer Pharmaceuticals Corporation | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
US7371763B2 (en) * | 2001-04-20 | 2008-05-13 | Bayer Pharmaceuticals Corporation | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas |
EP2295057B1 (en) * | 2001-12-03 | 2013-01-23 | Bayer HealthCare LLC | Aryl urea compounds in combination with other cytostatic or cytotoxic agents for treating human cancers |
US20080108672A1 (en) * | 2002-01-11 | 2008-05-08 | Bernd Riedl | Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors |
US20040023961A1 (en) * | 2002-02-11 | 2004-02-05 | Bayer Corporation | Aryl ureas with raf kinase and angiogenisis inhibiting activity |
AU2003209118A1 (en) | 2002-02-11 | 2003-09-04 | Bayer Pharmaceuticals Corporation | Aryl ureas as kinase inhibitors |
AU2003209119A1 (en) * | 2002-02-11 | 2003-09-04 | Bayer Pharmaceuticals Corporation | Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors |
EP2324825A1 (en) * | 2002-02-11 | 2011-05-25 | Bayer Healthcare LLC | Aryl ureas with angiogenesis inhibiting activity |
US7557129B2 (en) * | 2003-02-28 | 2009-07-07 | Bayer Healthcare Llc | Cyanopyridine derivatives useful in the treatment of cancer and other disorders |
DE602004011340T2 (de) * | 2003-05-20 | 2008-11-06 | Bayer Healthcare Llc | Diaryl-harnstoffe mit kinasehemmender wirkung |
PT1663978E (pt) * | 2003-07-23 | 2008-02-15 | Bayer Pharmaceuticals Corp | Omega-carboxiaril difenil ureia substituída por flúor para o tratamento e a prevenção de doenças e estados patológicos |
WO2005110994A2 (en) * | 2004-04-30 | 2005-11-24 | Bayer Pharmaceuticals Corporation | Substituted pyrazolyl urea derivatives useful in the treatment of cancer |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH452475A (de) * | 1965-05-20 | 1968-05-31 | Bayer Ag | Verfahren zum Färben und Bedrucken von synthetischem Textilmaterial mit Anthrachinonfarbstoffen |
-
1975
- 1975-03-11 US US05/555,307 patent/US4009847A/en not_active Expired - Lifetime
- 1975-03-26 SE SE7503523A patent/SE417965B/xx unknown
- 1975-04-15 CA CA224,634A patent/CA1047042A/en not_active Expired
- 1975-04-15 IL IL47095A patent/IL47095A/xx unknown
- 1975-04-16 NO NO751351A patent/NO144071C/no unknown
- 1975-04-16 PH PH17061A patent/PH11722A/en unknown
- 1975-04-16 FI FI751128A patent/FI751128A7/fi not_active Application Discontinuation
- 1975-04-16 FR FR7511796A patent/FR2267773B1/fr not_active Expired
- 1975-04-16 HU HU75DU237A patent/HU173052B/hu unknown
- 1975-04-16 DD DD185482A patent/DD117223A5/xx unknown
- 1975-04-16 YU YU00960/75A patent/YU96075A/xx unknown
- 1975-04-16 AR AR258396A patent/AR208545A1/es active
- 1975-04-16 ES ES436648A patent/ES436648A1/es not_active Expired
- 1975-04-16 DK DK164175A patent/DK164175A/da not_active IP Right Cessation
- 1975-04-16 DE DE19752516554 patent/DE2516554A1/de not_active Withdrawn
- 1975-04-16 GB GB1567175A patent/GB1461209A/en not_active Expired
- 1975-04-17 NL NL7504570A patent/NL7504570A/xx not_active Application Discontinuation
- 1975-04-17 JP JP50045924A patent/JPS50148349A/ja active Pending
- 1975-04-17 IE IE865/75A patent/IE41143B1/xx unknown
- 1975-04-17 CH CH494875A patent/CH611292A5/xx not_active IP Right Cessation
- 1975-04-17 LU LU72306A patent/LU72306A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SE417965B (sv) | 1981-04-27 |
SE7503523L (sv) | 1975-10-20 |
PH11722A (en) | 1978-05-30 |
NO144071B (no) | 1981-03-09 |
IE41143B1 (en) | 1979-10-24 |
DK164175A (da) | 1975-10-18 |
CH611292A5 (en]) | 1979-05-31 |
IL47095A (en) | 1978-03-10 |
FR2267773A1 (en]) | 1975-11-14 |
HU173052B (hu) | 1979-02-28 |
NL7504570A (nl) | 1975-10-21 |
NO751351L (en]) | 1975-10-20 |
FI751128A7 (en]) | 1975-10-18 |
IL47095A0 (en) | 1975-06-25 |
CA1047042A (en) | 1979-01-23 |
JPS50148349A (en]) | 1975-11-27 |
LU72306A1 (en]) | 1976-03-17 |
YU96075A (en) | 1983-04-27 |
AR208545A1 (es) | 1977-02-15 |
FR2267773B1 (en]) | 1978-08-18 |
IE41143L (en) | 1975-10-17 |
GB1461209A (en) | 1977-01-13 |
US4009847A (en) | 1977-03-01 |
AU8013575A (en) | 1976-10-21 |
DE2516554A1 (de) | 1975-10-30 |
DD117223A5 (en]) | 1976-01-05 |
NO144071C (no) | 1981-06-17 |
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